World’s fastest super-resolution microscope for cell biology and
neuroscience research now also offers quantitative functionality and
multimodal imaging
SAN DIEGO--(BUSINESS WIRE)--
At the 2015 Cell Biology ASCB Annual Meeting, Bruker (NASDAQ: BRKR)
today announced the release of the first quantitative super-resolution
microscope, the Vutara™
352. The Vutara 352 offers
speed, imaging depth, and resolution to deliver significant advantages
over competing approaches, now also adding real-time quantitative
capabilities. For the first time, this represents an entirely new
dimension of functionality in super-resolution microscopy, including the
ability to perform pair-correlation, co-location, cluster, and live-cell
analysis with super resolution.
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Bruker Introduces Vutara 352 Super-Resolution Fluorescence Microscope (Photo: Business Wire)
The Vutara 352 is now also compatible with Bruker’s Opterra
multi-point confocal microscope, creating a unique combination of
super-resolution and confocal capabilities, where both instruments are
designed for high-speed imaging. This enables the
visualization of large-scale, high-resolution structural context
in correlation with super-resolution imaging in even the most
challenging live-cell applications.
“Single molecule localization techniques are unique in that the images
are constructed from discrete, molecular-scale events,” explained
Stephen C. Minne, Ph.D., General Manager of Bruker's Fluorescence
Microscopy Business. “Unlike any other super-resolution system, the Vutara
352’s new proprietary algorithms leverage this benefit, enabling
researchers to conduct immediate quantitative analysis on their biology.
Only the Vutara 352 utilizes the highest 3D resolution to
quantify molecular co-location, or the fastest imaging speeds to
identify, track, and quantify fluorescent clusters in live-cells.”
“The Opterra-SR confocal scanner has provided us with a
significant enhancement to our Vutara system,” said Dr. Robert
Hobson from the Department of Biology at the University of Utah. “We can
now perform imaging across a range of modalities, including confocal
imaging and super-resolution imaging. The fast deconvolution of confocal
images provides us with a much clearer picture of samples of interest at
high resolution to complement our super-resolution imaging. The addition
of the quantitative analysis tools allows us to ask more detailed
empirical questions and obtain more rigorous results.”
About Vutara 352
Based on Bruker’s proprietary
biplane technology, Vutara 352 leverages high-performance
data acquisition and image processing capabilities to perform the entire
imaging workflow, from acquisition through localization to quantitative
analysis. Utilizing GPU processing, completion of an entire workflow
cycle can be accomplished in a matter of minutes, providing a
significant enhancement to work throughput. The Opterra SR
confocal scanner option, based on Bruker’s Opterra
II Microscope platform, adds additional imaging functionality to
the system, including real-time deconvolution. In addition to performing
standard fixed preparation and live-cell confocal imaging, Vutara
352 with the Opterra SR option enables seamless
correlative imaging to provide live, high-resolution imaging for sample
investigation prior to super-resolution imaging, as well as the
capability to combine super-resolution images with confocal images for
contextual information.
About Bruker Corporation
For more than 50 years, Bruker has
enabled scientists to make breakthrough discoveries and develop new
applications that improve the quality of human life. Bruker’s
high-performance scientific research instruments and high-value
analytical solutions enable scientists to explore life and materials at
molecular, cellular and microscopic levels.
In close cooperation with our customers, Bruker is enabling innovation,
productivity and customer success in life science molecular research, in
applied and pharma applications, in microscopy, nano-analysis and
industrial applications, as well as in cell biology, preclinical
imaging, clinical research, microbiology and molecular diagnostics. For
more information, please visit: http://www.bruker.com.
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Source: Bruker Corporation