High-Speed Confocal System Provides Most Quantitative and Flexible
Live-Cell Imaging
BILLERICA, Mass.--(BUSINESS WIRE)--
Bruker (NASDAQ: BRKR) today announced the release of the Opterra
II™ Multipoint Scanning Confocal Microscope, which
represents the next generation of quantitative live-cell microscopes.
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Bruker Opterra II Multipoint Scanning Confocal Microscope (Photo: Business Wire)
The Opterra II’s low photo-toxicity and photo-bleaching
capabilities deliver significant advantages over today’s spinning disk
confocal approaches, including enabling time-lapsed volumetric studies
on previously inaccessible specimens. This performance is achieved
through the system’s unique ability to optimize an experiment’s imaging
conditions through real-time adjustment of imaging speed, resolution,
and sensitivity. Additionally, the Opterra II provides
sub-10% field uniformity deviation, allowing quantitative analysis, in
all dimensions, as a standard feature.
“In a matter of a few hours after setup of the system we were collecting
publication-quality data with Opterra II,” said Dr.
William Bement, Chair of Laboratory Cell and Molecular Biology at the
University of Wisconsin, in Madison, WI. “The speed of the system,
coupled with its photo-activation capabilities allowed us to collect
data, and see interactions, that we had theorized about but had not seen
until now. Opterra II has allowed us to overcome obstacles
that have impeded our research for the past 5 years.”
“Making quantitative optical performance ‘standard,’ while enhancing the
microscope’s ease and flexibility of operation, all while expanding the
applications space into longer term live-cell studies, were our key
design challenges for the Opterra II,” explained Stephen
C. Minne, Ph.D., General Manager of Bruker's Fluorescence Microscopy
business. “Early customer feedback on the system’s performance, as well
as the versatility of its new high-speed filter wheel and bypass module,
is that the Opterra II is leap-frogging currently
available technology.”
About Opterra II
Opterra II is based on
Bruker’s patented multipoint confocal microscopy technology and
swept-field scanner. The new system provides next-generation
functionality compared to spinning disk systems through its ability to
tailor speed, resolution, and intensity to provide low photo-toxicity
and photo-bleaching on any biological specimen. The Opterra II
also features a sub-10% field illumination uniformity; options for
bypass capability for wide-field, bright-field, and TIRF imaging; a
high-speed 10-position filter wheel; as well as photo-activation,
spectral imaging and un-mixing capabilities.
About Bruker Corporation
For more than 50 years, Bruker has
enabled scientists to make breakthrough discoveries and develop new
applications that improve the quality of human life. Bruker’s
high-performance scientific research instruments and high-value
analytical solutions enable scientists to explore life and materials at
molecular, cellular and microscopic levels.
In close cooperation with our customers, Bruker is enabling innovation,
productivity and customer success in life science molecular research, in
applied and pharma applications, in microscopy, nano-analysis and
industrial applications, as well as in cell biology, preclinical
imaging, clinical research, microbiology and molecular diagnostics. For
more information, please visit: http://www.bruker.com.
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Source: Bruker Corporation